Of those who used them exclusively for weight loss, the majority (91.4% [85.697.2%]) reported using medications licensed for this purpose in Great Britain, most commonly Mounjaro (tirzepatide
Wild B, Hnnemeyer K, Sauer H, Hain B, Mack I, Schellberg D, et al
Vitamin B12 deficiency is more prevalent than many people realise: Around 6% of the UK population has B12 deficiency This rises to approximately 20% in those over 60 An estimated 1 in 10 people in the UK may have inadequate B12 levels 6% of men and 10% of women aged 19-64 have low serum B12 concentrations Among women of reproductive age (19-49), 11% have low B12 Interestingly, research suggests that deficiency is often due to absorption problems rather than dietary intake
Metformin Metformin is not FDA-approved for weight loss, but it produces modest weight reduction (2-3% of body weight) as a side effect of its primary mechanism, improving insulin sensitivity and reducing hepatic glucose production
These may be temporary and resolve without any medication changes
Key Takeaways Retatrutide is a triple hormone receptor agonist that targets both fat loss and muscle preservation, enabling weight management for obesity