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Preclinical safety data In mouse studies, 5-amino-1mq was well-tolerated even at doses several times higher than those producing metabolic effects
Intermediate users may increase the dose to 400500 micrograms daily
doi:10.1046/j.1365-2230.2002.01076.x [49] Abu-Ouf NM, Jan MM
Experimental findings indicate that the compound may trigger cellular mechanisms that release fatty acids from fat stores without significantly altering insulin or IGF-1 levels
The remaining 3 studies, scored eight and nine, indicating high-quality studies with low risk of bias (Table 5)
Niacin/niacinamide may potentiate the effects of antihypertensive medications by causing additional vasodilation
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