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Indications: FDA approved: Type II diabetes - monotherapy or combination therapy Can be combined as adjunct therapy with other hypoglycemics including metformin, thiazolidinediones, or insulin regimens (Dungan & DeSantis 2015) Because it does not work when your blood sugar is low, it is unlikely to produce dangerous levels of hypoglycemia has been observed in clinical trials (in contrast to GLP-1 incretin mimetics, such as exenatide, which produce moderate weight loss)
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The Medicines and Healthcare products Regulatory Agency assesses whether the medication is safe and effective enough to be licensed for UK use
The mechanism of action centres on mimicking the naturally occurring hormone GLP-1, which is released from the intestine in response to food intake
It establishes the scientific rationale for targeting cellular senescence as a driver of aging and age-related diseases
